Study Condition(s): Ulcerative Colitis

A Study of LY3074828 in Participants With Moderate to Severe Ulcerative Colitis

Study Alias: AMAC

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02589665 {{ currentLocaleObject.registryAnchorText }}

Recruiting Recruiting

Study Purpose

The main purpose of this study is to test the hypothesis that treatment with LY3074828 is superior to placebo in providing clinical benefit to participants with moderate to severe ulcerative colitis (UC). This study will also investigate how the body processes the drug.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18 years
75 years

Time Commitment

Your participation could last up to 1 year and include 32 visits to the study center.
  • Participant must have moderate to severe active ulcerative colitis (UC)

  • Participant must have evidence of ulcerative colitis extending near the rectum

  • Participant must not have been diagnosed with Crohn's Disease, indeterminate colitis or proctitis

  • Participant must not have had surgery for the treatment of ulcerative colitis or be likely to require surgery for ulcerative colitis during the study

  • Participant must not have received any of the following for treatment of ulcerative colitis: cyclosporine or thalidomide, corticosteroid enemas, corticosteroid suppositories, or topical treatment with 5-aminosalicyclic acid within 30 days of screening

Where to Participate

41 locations are currently available of 70 planned
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