Study Condition(s): Type 2 Diabetes

A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes (PRONTO-T2D)

Study Alias: ITRN

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT03214380 {{ currentLocaleObject.registryAnchorText }}

Recruiting Recruiting

Study Purpose

The purpose of this study is to compare LY900014 to insulin lispro, both in combination with insulin glargine or insulin degludec, in participants with type 2 diabetes (T2D).

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Your participation in the main study could last up to 39 weeks. At the end of this period, you may be asked to return for additional follow-up blood tests for up to 26 weeks.
  • Participant must have been diagnosed with type 2 diabetes at least 1 year ago
  • Participant must have been treated with one of the following for at least 90 days prior to starting the study:

          Basal insulin (insulin glargine U-100 [Basaglar/Abasaglar or LANTUS] or U-300,
          insulin detemir, insulin degludec U-100 or U-200, or neutral protamine Hagedorn
          [NPH] insulin) in combination with at least 1 prandial injection of bolus insulin
          (insulin lispro U-100 or U-200, insulin aspart, insulin glulisine, or regular
          insulin)
    
          OR
    
          Premixed analog or human insulin regimens with any basal and bolus insulin
          combination injected at least twice daily
  • Participant must not have been diagnosed with type 1 diabetes or latent autoimmune diabetes in adults

  • Participant must not have had emergency treatment for very low blood glucose or poor blood gluecose control in the last 6 months
  • Participant must not have used thiazolidinediones, Glucagon-Like Peptide 1 (GLP-1) receptor agonist, or pramlintide within the last 90 days

Where to Participate

115 locations are currently available of 115 planned
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