Study Condition(s): Terminal Illness
A 18F-AV-1451 Autopsy Study
Study Alias: 1451
The purpose of this study is to test the relationship between ante-mortem 18F-AV-1451 Positron Emission Tomography (PET) imaging and tau neurofibrillary pathology associated with Alzheimer's disease (AD), as measured at autopsy.
The results of this study are not yet available.
Here you can find out a bit more about the requirements for volunteers who took part in this study
- Participant must have a projected life expectancy of ≤ 6 months
- Participant must be able to tolerate a 20 minute Positron Emission Tomography (PET) scan
- Participant must give informed consent or have a legally authorized representative to consent for study procedures and brain donation consistent with the legal requirements of the State in which they die
- Participant must not be undergoing aggressive treatment with life sustaining measures
- Participant must not have a known structural brain lesion that would interfere either with PET imaging or pathological assessment
- Participant must not be currently receiving any investigational medications except with permission from the study sponsor
- Participant must not have previously participated in an experimental study with an amyloid or tau targeting agent
- Participant must not have a suspected disorder of the brain due to alcoholism or end-stage liver disease
- Female participant must not be of childbearing potential