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Systemic Juvenile Idiopathic Arthritis

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With sJIA

JAHU | {{ defaultRegistry.registryAnchorText }} NCT04088396 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The reason for this study is to see if the study drug baricitinib is safe and effective in participants from 1 year to less than 18 years old with systemic juvenile idiopathic arthritis (sJIA).

Time Commitment

The study will last about 164 weeks and may include up to 30 visits.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria


Male Female


1 year
17 years

-Participants must have systemic Juvenile Idiopathic Arthritis (sJIA) with onset before the age of 16 years

-Participants must have arthritis in 1 or more joints with or preceded by fever of at least 2 weeks’ duration that is documented to be daily (quotidian) fever for at least 3 days, and accompanied by 1 or more of the following:

-Evanescent (nonfixed) erythematous rash

-Generalized lymph node enlargement

-Hepatomegaly and/or splenomegaly


-Participants must have at least 2 active joints

-Participants must not have polyarticular JIA, extended oligoarticular JIA, enthesitis-related JIA or juvenile psoriatic arthritis

-Participants must not have persistent oligoarticular arthritis

-Participants must not have any autoimmune inflammatory condition other than JIA

-Participants must not have active anterior uveitis

-Participants must not have active fibromyalgia or other chronic pain conditions

-Participants must not have an infection

-Participants must not have hepatitis B or tuberculosis (TB)

Where to Participate

Where to Participate

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