Study Condition(s): Esophageal Cancer, Non-small Cell Lung Cancer, Stomach Cancer, Gastroesophageal Junction Cancer (GEJ)

A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Study Alias: JVDJ

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02572687 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to evaluate the safety of ramucirumab plus MEDI4736 in participants with locally advanced and unresectable or metastatic gastrointestinal or thoracic malignancies including gastric or gastroesophageal junction (GEJ) adenocarcinoma, non-small cell lung cancer (NSCLC), or hepatocellular carcinoma (HCC)

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Your participation could range from several months to several years depending on how you and your tumor respond
  • Participant must have measurable metastatic disease or locally advanced and unresectable disease

  • Participant must be willing to provide tumor tissue for biomarker analysis

  • Participant must not have known brain metastases

  • Participant must not have active or prior documented autoimmune disease within the past 24 months

  • Participant must not have HIV, AIDS-related illness, or a history of immunodeficiency

  • Participant with hepatitis B or hepatitis C infection may not be eligible depending on your tumor type

Where to Participate

20 locations are currently available of 20 planned
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