Study Condition(s): Solid Tumor

A Study of LY3415244 in Participants With Advanced Solid Tumors

Study Alias: JZDA

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT03752177 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The goal of this study is to evaluate the safety of LY3415244 administered as monotherapy to participants with advanced solid tumors.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Participation in this trial will last at least 8 weeks and possibly longer if your disease does not progress.
  • Participant must have an advanced solid tumor confirmed by histology or cytology

  • Participant must be willing to provide a newly obtained biopsy prior to and during study

  • Participant must have an estimated life expectancy of at least 12 weeks

  • Participant must not have symptoms of uncontrolled brain metastases, spinal cord compression, or leptomeningeal disease that requires treatment occurring at the same time as the study treatment

  • Participant must not have received a live vaccine within 30 days before the first dose of study treatment

  • Female participant must not be pregnant, breastfeeding, or planning to become pregnant

  • Participant must not have active or chronic HIV, active hepatitis B virus (HBV), active hepatitis C virus (HCV), active autoimmune disorders, or prior documented severe autoimmune or inflammatory disorders requiring immunosuppressive treatment

  • Participant must not have a bowel obstruction

  • Participant must not have moderate to severe cardiovascular disease

Where to Participate

6 locations are currently available of 6 planned
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