Study Condition(s): Psoriasis, Psoriatic Arthritis

A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis (SPIRIT P3)

Study Alias: RHBF

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02584855 {{ currentLocaleObject.registryAnchorText }}

Withdrawn Active, not recruiting

Study Purpose

The main purpose of this study is to evaluate the safety and long-term efficacy of ixekizumab compared to placebo in participants with active psoriatic arthritis.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Your participation could last up to 2.5 years and include 32 visits to the study center.
  • Participant must have a diagnosis of active psoriatic arthritis (PsA) for at least 6 months. Active PsA is defined as the presence of at least 3 tender and at least 3 swollen joints

  • Participant must have the presence of active psoriatic skin lesions or a history of plaque psoriasis (Ps)

  • Male participants must agree to use a reliable method of birth control or remain abstinent during the study

  • Female participants must agree to use reliable method of birth control or remain abstinent during the study and for at least 12 weeks after stopping treatment

  • Participant must have been previously treated with 1 or more conventional disease-modifying antirheumatic drugs (cDMARDs)

  • Participant must not be currently using more than one cDMARD

  • Participant must not have current or prior use of biologic agents for treatment of Ps or PsA

  • Participant must not have a diagnosis of active inflammatory arthritic syndromes or spondyloarthropathies other than PsA

  • Participant must not have received treatment with interleukin (IL) -17 or IL12/23 targeted monoclonal antibody (MAb) therapy

  • Female participant must not be pregnant or breastfeeding

Where to Participate

121 locations are currently available of 122 planned
Invalid Postal Code.
Please re-enter postal code.

{{sites.getPageStartCount()}} - {{sites.getPageEndCount()}} of {{sites.totalCount}} Results

0 of {{sites.totalCount}} Results

Distance Location Status
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
,
Status {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus | translate}}
Closest Location to Participate
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
,
Status {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus | translate}}
Other Location(s) to Participate
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
,
Status {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus}} {{site.siteStatus | translate}} {{site.getSiteCTALabel() | translate}}

To improve your experience on Lilly TrialGuide, please use the latest version of Chrome, Firefox, Safari, or Internet Explorer, with Java Script enabled.
This website is not optimized for your browser, as configured.