Study Condition(s): Psoriasis

A Study of Ixekizumab (LY2439821) Compared to Guselkumab in Participants With Moderate-to-Severe Plaque Psoriasis

Study Alias: RHCR

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT03573323 {{ currentLocaleObject.registryAnchorText }}

Withdrawn Not yet recruiting

Study Purpose

The purpose of this study is to compare the efficacy and safety of ixekizumab to guselkumab in participants with moderate-to-severe plaque psoriasis.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

The study will last about 24 weeks and may include up to 12 visits (follow up includes up to 3 visits).

-Participants must have chronic plaque psoriasis diagnosed for at least 6 months before to participate in the study -Participants must have >=10% body surface area involvement -Participants must agree to use highly effective method of contraception -Participants must not have predominant pattern of pustular, erythrodermic, and/or guttate forms of psoriasis -Participants must not have a history of drug-induced psoriasis -Participants must not have used tanning booths for at least 4 weeks before baseline -Participants must not have previous use of guselkusemab -Participants must not have previously participated in any other study with ixekizumab, or any other IL-17 or IL-23 antagonists, or have received treatment with other IL-17 or IL-23 antagonists -Participants must not have a known allergy or hypersensitivity to any biologic therapy

Where to Participate

0 locations are currently available of 140 planned
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