Study Condition(s): Prostate Cancer

A Study of Enzalutamide and LY3023414 in Men with Prostate Cancer

Study Alias: CBBD

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02407054 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in men with prostate cancer.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria




18+ years

Time Commitment

Your participation could last up to 56 days or longer if you are tolerating the study drug and your study doctor thinks your condition is stable or improving.
  • Participant must have diagnosis of prostate cancer

  • Participant must have metastatic disease

  • Participant must have completed and failed prior abiraterone treatment

  • Participant must be surgically or medically castrated

  • Participant must be able to swallow the study drug (pills) whole

  • Participant must not have had prior treatment with chemotherapy or enzalutamide

  • Participant must not have known brain metastases or uncontrolled hypertension

  • Participant must not have insulin-dependent diabetes mellitus, however participants with type 2 diabetes mellitus may be eligible

  • Participant must not have an active, known fungal, bacterial, and/or known viral infection

Where to Participate

50 locations are currently available of 50 planned
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