Study Condition(s): Pancreatic Ductal Adenocarcinoma

A Study of Abemaciclib (LY2835219) Alone or in Combination with Other Agents in Participants with Previously Treated Pancreatic Ductal Adenocarcinoma

Study Alias: JPCJ

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02981342 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The purpose of this study is to evaluate the safety and efficacy of abemaciclib alone and in combination with other drugs versus standard of care in participants with previously treated metastatic pancreatic ductal adenocarcinoma (PDAC).

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

The duration of your participation depends on how well your disease responds to the study treatment and how many cycles of treatment you receive.
  • Participant must have histological or cytological diagnosis of ductal adenocarcinoma of the pancreas
  • Participant must have adequate organ function
  • Participant must not have insulin-dependent diabetes mellitus
  • Participant must not have previously received treatment with any cyclin-dependent kinase (CDK) 4 and 6 inhibitor or phosphatidylinositol 3-kinase (PI3K) and/or mammalian target of rapamycin (mTOR) inhibitor

Where to Participate

41 locations are currently available of 41 planned
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