Study Condition(s): Non-small Cell Lung Cancer

A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer

Study Alias: JPBX

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02450539 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to evaluate the effectiveness of the study drug known as abemaciclib versus docetaxel in participants with stage IV squamous non-small cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

You can participate in this study for as long as your study doctor determines that you are benefiting from the study treatment
  • Participant must have a confirmed diagnosis of stage IV Squamous NSCLC

  • Participant must have progressed during or after platinum-based chemotherapy

  • Participant must not have received prior treatment with docetaxel

  • Participant must be fully active or if restricted in physically strenuous activity should be able to walk and carry out light work, e.g., light house work, office work

  • Participant must agree to use a reliable medically approved method of birth control

  • Participant must not have received prior treatment with any cyclin dependent kinase (CDK) 4 and 6 inhibitor or participated in a clinical trial with a CDK 4 and 6 inhibitor where the treatment administered is not known

  • Participant must not be currently receiving treatment in a clinical trial involving an investigational product or non-approved use of a drug or device

Where to Participate

51 locations are currently available of 51 planned
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