Back to search results

Head and Neck Cancer

A Study of Prexasertib (LY2606368) with Chemotherapy and Radiation in Participants with Head and Neck Cancer

JTJI | {{ defaultRegistry.registryAnchorText }} NCT02555644 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to investigate the safety of prexasertib (LY2606368) in combination with other anti-cancer drugs (cisplatin or cetuximab) and radiation therapy in participants with locally advanced head and neck cancer. The study has two parts (A and B). Participants will only enroll in one part.

Completed Study

The results of this study are not yet available.

Time Commitment

Your participation will last ~ 7-8 weeks depending on how well you tolerate therapy. There is also a follow up period of ~ 1 year.

Who Participated? Tool Tip Icon

Here you can find out a bit more about the requirements for volunteers who took part in this study


Male Female


18+ years
  • Participant must have a diagnosis of head and neck squamous cell carcinoma of the oropharynx (tonsil, base of tongue, soft palate, or oropharyngeal walls), hypopharynx, or larynx

  • Participants of reproductive potential must agree to use medically approved contraceptive precautions during the study and for six months following the last dose of study drug

  • Female participants of childbearing potential must have negative pregnancy test and must not be breast feeding

  • Participant must not have received any of the following prior therapies or treatments: systemic therapy for the head and neck cancer, radiation therapy to the head and neck region, or curative-intent surgery in the head and neck region

  • Participant must not have an active symptomatic fungal, bacterial or viral infection, including HIV or Hepatitis A, B, or C

  • Participant must not have a serious heart condition, such as congestive heart failure, unstable angina pectoris, or have had a heart attack within the last three months

Where This Study Took Place Tool Tip Icon

Where This Study Took Place Tool Tip Icon

Invalid Postal Code.
Please re-enter postal code.

{{sites.getPageStartCount()}} - {{sites.getPageEndCount()}} of {{sites.totalCount}} Results

0 of {{sites.totalCount}} Results

Distance Location
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
Closest Location
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
Other Location(s)
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}

To improve your experience on Lilly TrialGuide, please use the latest version of Chrome, Firefox, Safari, or Internet Explorer, with Java Script enabled.
This website is not optimized for your browser, as configured.