Study Condition(s): Genital Psoriasis, Psoriasis

A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Genital Psoriasis (IXORA-Q)

Study Alias: RHBQ

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02718898 {{ currentLocaleObject.registryAnchorText }}

Withdrawn Active, not recruiting

Study Purpose

The main purpose of this study is to evaluate the efficacy and safety of the study drug ixekizumab compared to placebo in participants with moderate-to-severe genital psoriasis.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria


Male Female


18+ years

Time Commitment

Your participation could last up to 16 months and include 15 visits to the study center
  • Particpant must have a diagnosis of chronic plaque psoriasis for at least 6 months before entering the study

  • Participant must have moderate-to-severe psoriasis in the genital area at the time of entering the study

  • Participant must also have plaque psoriasis in a non-genital area at the time of entering the study

  • Participant must have failed to respond to, or are intolerant of, at least 1 topical therapy used for treatment of psoriasis affecting the genital area

  • Participant must agree to use reliable method of birth control, which could include abstinence, during the study and for at least 12 weeks following the last dose of study drug

  • Participant must not have Pustular, erythrodermic, and/or guttate forms of psoriasis or a history of drug-induced psoriasis

  • Participant must not have ever received treatment with ixekizumab, secukinumab, brodalumab, or another drug with a similar mode of action

  • Participant must avoid excessive sun exposure or use of tanning booths for at least 4 weeks prior to baseline and during the study

  • Participant must not currently have cancer or have had cancer within 5 years prior to baseline

  • Female participants must not be pregnant or breastfeeding

Where to Participate

33 locations are currently available of 40 planned
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