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Recruiting

Metastatic Breast Cancer

A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer

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Study Purpose

The reason for this study is to see if the study drug LY3484356 alone or in combination with abemaciclib is safe and effective in participants with advanced or metastatic breast cancer.

Time Commitment

Your participation in this trial could last up to 42 months, depending on your cancer type and how you and your tumor respond

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

-Participants must have estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) breast cancer that may have spread to other part(s) of the body and has had at least 1 line of standard therapy

-Participants must be willing to have new tumor tissue biopsies (doctor removes a small amount of tissue) during the study if it does not cause undue risks to health

-Participants must be willing to use highly effective birth control

-Participants must have adequate organ function

-Participants must be able to swallow capsules

-Participants must not have certain infections such as hepatitis or tuberculosis or HIV that are not well controlled

-Participants must not have another serious medical condition

-Participants must not have cancer of the central nervous system that is not stable

-Participants must not be pregnant or breastfeeding

Where to Participate

Where to Participate

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