Back to search results

Atopic Dermatitis (Eczema)

A Study of LY3454738 in Healthy Participants and Participants With Atopic Dermatitis (Eczema)

FRCC | {{ defaultRegistry.registryAnchorText }} NCT03750643 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to investigate the safety, tolerability, and efficacy of the study drug known as LY3454738 in healthy participants and participants with atopic dermatitis (eczema). The study has three parts. Each participant will enroll in one part. The study will last 12 to 24 weeks, depending on part.

Time Commitment

The study will last up to 24 week and may include up to 12 visits.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria


Male Female


18 years
65 years
  • Participants must weigh at least 110 pounds (50 kilograms)
  • Japanese participants must have all biological parents and grandparents born in Japan and be of exclusive Japanese descent
  • Participants with atopic dermatitis (AD) must have a diagnosis of AD for at least 12 months. The disease symptoms must be severe enough that they do not respond well to medicines that are applied to the skin
  • Participants with AD must agree to use moisturizer daily
  • Participants must not have received certain “biologic” medications in a specific time frame. This will be discussed with the study doctor.
  • Participants with AD must not have received steroids (except those applied to the skin) in the past 6 weeks prior to randomization

Where to Participate

Where to Participate

Invalid Postal Code.
Please re-enter postal code.

{{sites.getPageStartCount()}} - {{sites.getPageEndCount()}} of {{sites.totalCount}} Results

0 of {{sites.totalCount}} Results

Distance Location Status
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
{{site.siteStatus | translate}}
Closest Location to Participate
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
{{site.siteStatus | translate}}
Other Location(s) to Participate
{{site.getDistance() | number:0}} {{convertUnit("imperial", "mile") | translate}} {{convertUnit("imperial", "miles") | translate}}
{{site.siteStatus | translate}}

To improve your experience on Lilly TrialGuide, please use the latest version of Chrome, Firefox, Safari, or Internet Explorer, with Java Script enabled.
This website is not optimized for your browser, as configured.