Study Condition(s): Advanced Cancer

A Study of LY3405105 in Participants With Advanced Cancer

Study Alias: JZFA

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT03770494 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The main purpose of this study is to investigate the safety of LY3405105 in participants with advanced cancer. The study has two parts (A and B). Participants will only enroll in one part.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Your participation in this trial could last 6 months or longer depending on how you and your tumor respond.
  • Participants must have evidence of a diagnosis of a solid tumor cancer that is advanced and/or metastatic

  • Participants must have available archived tissue for exploratory biomarker analysis

  • Participants must have adequate organ function

  • Participants must have discontinued all previous treatments for cancer and recovered from their side effects

  • Participants must be able to swallow capsules/tablets

-Participants must not have symptomatic central nervous system (CNS) malignancy or metastasis

-Participants must not have symptomatic HIV, Hepatitis A, B, or C

-Participants must not have congestive heart failure

-Participants must not be breastfeeding

Where to Participate

5 locations are currently available of 10 planned
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