Study Condition(s): Advanced Cancer, Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Metastatic Melanoma, Non-small Cell Lung Cancer

A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer

Study Alias: JUAB

Study Identifier(s): Tool Tip Icon {{ defaultRegistry.registryAnchorText }} NCT02857270 {{ currentLocaleObject.registryAnchorText }}

Study Purpose

The purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other agents in participants with advanced cancer.

Key Participation Requirements Tool Tip Icon

All clinical trials have rules about who can participate. This section outlines some of those rules. Please contact a study center to discuss the full set of criteria

Gender

Male Female

Age

18+ years

Time Commitment

Your participation may continue for as long as you and your study doctor feel that you are benefiting from the study treatment.
  • Participant must have advanced, unresectable or metastatic cancer (solid tumors)
  • Participant must not have known HIV infection or hepatitis A, B, or C
  • Participant must not have current blood cancers, acute or chronic leukemia
  • Participant must not have previously completed or withdrawn from this study or any other study investigating an ERK1/2 inhibitor
  • Female participant must not be pregnant, breastfeeding, or planning to become pregnant

Where to Participate

7 locations are currently available of 7 planned
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